SCHEMBL22414653

SCHEMBL22414653

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4oc5c6ccccc6c6ccccc6c5c4c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 5/20 0.40
▸ PLA2G4A P47712 5/20 0.40
▸ KDM4E B2RXH2 3/20 0.37
▸ MAPT P10636 3/20 0.37
▸ L3MBTL1 Q9Y468 3/20 0.37
▸ GAA P10253 3/20 0.37
▸ CYP3A4 P08684 2/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ CASP3 P42574 2/20 0.37
▸ ALPI P09923 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ CASP6 P55212 1/20 0.37
▸ MCL1 Q07820 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ PLA2G10 O15496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25903184 0.90 PLA2G2A (0.40) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL17658480 0.89 KDM4E (0.33) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL17740686 0.89 PLA2G2A (0.37) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL24527214 0.89 KDM4E (0.34) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL20109551 0.88 MEN1 (0.35) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL21795022 0.88 PLA2G2A (0.49) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL17658482 0.88 PLA2G2A (0.35) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL17658415 0.88 MEN1 (0.32) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL20845453 0.87 CCNC (0.35) PLA2G2APLA2G4AKDM4EMAPTL3MBTL1
SCHEMBL17658565 0.87 KDM4E (0.38) KDM4EMAPTL3MBTL1GAACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127951-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-04-27 — — US disclosed
US-20230127951-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-04-27 — — US disclosed
US-20200283426-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127951-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLCO2A1 PLA2G2A 4628/4885PLA2G4A 4829/4885KDM4E 1689/4885
US-20200283426-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USE1, SLC16A1, SLCO4C1 PLA2G2A 4625/4885PLA2G4A 4841/4885KDM4E 2443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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