Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010674 | 1.00 | CCNT1 (0.39) | CCNT1CDK9TLR7NTRK1MAPK11 | |
| SCHEMBL21936084 | 0.85 | NTRK1 (0.43) | CCNT1CDK9TLR7NTRK1TLR9 | |
| SCHEMBL13858452 | 0.85 | NTRK1 (0.43) | CCNT1CDK9TLR7NTRK1TLR9 | |
| SCHEMBL22415996 | 0.84 | MAPK11 (0.44) | TLR7MAPK11MAPK14TLR9TLR8 | |
| SCHEMBL28210779 | 0.80 | MAPK11 (0.49) | MAPK11MAPK14 | |
| SCHEMBL21147738 | 0.80 | DRD2 (0.51) | — | |
| SCHEMBL30010653 | 0.80 | DRD2 (0.51) | — | |
| SCHEMBL13974997 | 0.80 | DRD2 (0.51) | — | |
| SCHEMBL13974510 | 0.80 | TLR9 (0.40) | CCNT1CDK9TLR7NTRK1TLR9 | |
| SCHEMBL30010274 | 0.79 | DRD2 (0.50) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409670-B1 | N-PYRROLIDINYL, N'-PYRAZOLYL- UREA COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2020-09-09 | — | — | EP | disclosed |