Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785800 | 0.88 | POLB (0.43) | CA12CA1CA9CYP1A2MAPT | |
| SCHEMBL3778070 | 0.88 | POLB (0.43) | CA12CA1CA9CYP1A2MAPT | |
| SCHEMBL3778074 | 0.88 | POLB (0.43) | CA12CA1CA9CYP1A2MAPT | |
| SCHEMBL22416591 | 0.87 | RARA (0.39) | CA12CA1CA9NR1H4MAPT | |
| SCHEMBL20143603 | 0.84 | MAPT (0.47) | CA12CA9NR1H4MAPTALDH1A1 | |
| SCHEMBL16355696 | 0.84 | MAPT (0.47) | CA12CA9NR1H4MAPTALDH1A1 | |
| SCHEMBL15876021 | 0.84 | MAPT (0.47) | CA12CA9NR1H4MAPTALDH1A1 | |
| SCHEMBL509152 | 0.82 | CA12 (0.53) | CA12CA1CA9RXRBNR1H4 | |
| SCHEMBL22398438 | 0.82 | MAPT (0.37) | CA12CA1CA9CYP1A2MAPT | |
| SCHEMBL22416660 | 0.82 | RAB9A (0.37) | CA12CA1CA9NR1H4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705471-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | UBE Industries, Ltd. (JP) | 2020-09-09 | — | — | EP | disclosed |