Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086490 | 0.80 | MAPT (0.36) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL19380418 | 0.72 | TSHR (0.36) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL18535999 | 0.72 | ALPG (0.43) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20860970 | 0.71 | TSHR (0.35) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL18900710 | 0.70 | MAOB (0.37) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL1610145 | 0.70 | MAPT (0.50) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21253839 | 0.69 | MAOB (0.35) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20123086 | 0.69 | CSNK2A2 (0.36) | MAPTHTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23018699 | 0.68 | CA2 (0.35) | — | |
| SCHEMBL24363331 | 0.67 | MAPT (0.35) | MAPTHTTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034582-B1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2020-09-09 | — | — | EP | disclosed |