Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920351 | 0.94 | MTNR1A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL22475346 | 0.91 | NPC1 (0.33) | MTNR1AMTNR1B | |
| SCHEMBL21905015 | 0.90 | CYP3A4 (0.38) | MTNR1AMTNR1BCYP3A4CYP2D6 | |
| SCHEMBL21163118 | 0.90 | MTNR1A (0.34) | MTNR1AMTNR1BCYP3A4CYP2D6 | |
| SCHEMBL22417644 | 0.88 | MTNR1A (0.31) | MTNR1AMTNR1BCYP3A4CYP2D6 | |
| SCHEMBL17213612 | 0.83 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL11920355 | 0.83 | TSHR (0.35) | — | |
| SCHEMBL22417567 | 0.82 | CYP3A4 (0.38) | MTNR1AMTNR1BCYP3A4CYP2D6 | |
| SCHEMBL22475348 | 0.82 | AR (0.36) | MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL22417598 | 0.82 | AR (0.36) | MTNR1AMTNR1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2965742-B1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-09 | — | — | EP | disclosed |