Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | GLI2 | P10070 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166853 | 0.88 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL4463432 | 0.88 | KDM4E (0.50) | SLC6A2SLC6A4SLC6A3MAPTNPSR1 | |
| SCHEMBL27654632 | 0.81 | NPC1 (0.49) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL3632143 | 0.80 | USP2 (0.48) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL4362240 | 0.78 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL9717426 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL28166707 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL28131512 | 0.75 | MAOA (0.49) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL15253052 | 0.74 | MAOA (0.51) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A | |
| SCHEMBL8531102 | 0.74 | NPC1 (0.43) | SLC6A2SLC6A4SLC6A3CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020184670-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | 大塚製薬株式会社 | 2020-09-17 | — | — | WO | disclosed |
| CN-1921846-A | Combinatorial therapy with an acetylcholinesterase inhibitor and (3AR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate | AXONYX INC (US) | 2007-02-28 | — | — | CN | disclosed |