Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28902200 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL465429 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17628648 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28397286 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL210852 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1194495 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10945724 | 0.97 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5082394 | 0.93 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27290773 | 0.93 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.93 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 58846 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117058976-B | Folding display device, optical cement and manufacturing method thereof | BOE Technology Group Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-118878818-B | Method for preparing regenerated polyesteramide based on ester-amide exchange reaction | DONGHUA UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4745177-A1 | METHOD FOR PRODUCING CROSSLINKABLE POLYESTER COMPOSITION | Nagoya Institute Of Technology (JP) | 2026-05-20 | — | — | EP | claimed |
| CN-122037150-A | Method for preparing polyether ester thermoplastic elastomer based on aromatic polyester | 苏州大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4741448-A1 | HEAT-SHRINKABLE POLYESTER FILM | Toyobo Co., Ltd. (JP) | 2026-05-13 | — | — | EP | claimed |
| EP-4741530-A1 | RESIN-COATED SEAMLESS ALUMINUM CAN, RESIN-COATED ALUMINUM SHEET, AND DRAWN-IRONED CAN | Toyo Kohan Co., Ltd. (JP) | 2026-05-13 | — | — | EP | claimed |
| CN-122011348-A | Hydrolysis-resistant crystallizable copolyester material, and preparation method and application thereof | 氧倍加新材料科技(金华)有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-116096551-B | Heat-shrinkable polyester film, heat-shrinkable label, and package | 东洋纺株式会社 | 2026-05-12 | — | — | CN | claimed |
| US-20260110701-A1 | METHODS OF DETECTING MICROPLASTICS IN BIOLOGICAL SAMPLES | CONTIGUOUS LABS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4727997-A1 | PROCESS FOR RECYCLING OF A COLORED POLYMERIC MATERIAL AND EXTRUSION PRODUCT OBTAINED THEREFROM | BASF SE (DE) | 2026-04-22 | — | — | EP | claimed |
| US-3970635-A | 1,3-DIOXAPHOSPHOLANE OXIDES | MONSANTO COMPANY (US) | 1976-07-20 | — | — | US | claimed |
| US-3967027-A | Stable electret retaining a high surface potential and method of making the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-06-29 | — | — | US | claimed |
| US-3962152-A | SURFACTANT, ETHYLENE TEREPHTHALATE, POLYETHYLENE OXIDE TEREPHTHALATE | THE PROCTER & GAMBLE COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3962185-A | POLYESTER COMPOSITIONS HAVING A DURABLE ANTISTATIC PROPERTY | MITSUBISHI RAYON CO., LTD. (JA) | 1976-06-08 | — | — | US | claimed |
| US-3960686-A | ETHYLENE TEREPHTHALATE, A SUBSTITUTED CYCLOBUTANEDIMETHANOL | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | claimed |
| US-3959230-A | SOIL RELEASE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| US-3953405-A | Method for preparing low pilling effect polyester fiber products | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT | 1976-04-27 | — | — | US | claimed |
| US-3951905-A | ANTIMONY CONTAINING PARTICLES | TORAY INDUSTRIES, INC. (JA) | 1976-04-20 | — | — | US | claimed |
| US-3947872-A | Process for thermoremanent duplication of magnetic recording master tape onto slave tape with reduced dimensional changes of slave tape | TEIJIN LTD. (JA) | 1976-03-30 | — | — | US | claimed |
| US-3946091-A | POLYETHYLENE TEREPHTHALATE | UNITIKA LIMITED (JA) | 1976-03-23 | — | — | US | claimed |