Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.86 |
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28902200 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL465429 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL17628648 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL22420 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL210852 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1194495 | 1.00 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10945724 | 0.97 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5082394 | 0.93 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27290773 | 0.93 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.93 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107179661-B | Metal toner composition | 施乐公司 | 2020-04-17 | — | — | CN | disclosed |