Terephthalic Acid

Terephthalic Acid

SCHEMBL465429

C=C.C=C.C=C.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.86
TP53 P04637 1/20 0.86
SRD5A2 P31213 4/20 0.71
CA1 P00915 3/20 0.67
CA2 P00918 3/20 0.67
CA12 O43570 1/20 0.67
CA3 P07451 1/20 0.67
TYR P14679 1/20 0.67
DRD1 P21728 1/20 0.67
CA4 P22748 1/20 0.67
CA6 P23280 1/20 0.67
CA5A P35218 1/20 0.67
CA7 P43166 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
NAPRT Q6XQN6 2/20 0.65
DAO P14920 1/20 0.65
ALDH1A1 P00352 2/20 0.63
ALOX15 P16050 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28902200 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL17628648 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL22420 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28397286 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL210852 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL1194495 1.00 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL10945724 0.97 TSHR (0.80) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL5082394 0.93 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL27290773 0.93 TSHR (0.86) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL2511919 0.93 TSHR (1.00) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220212456-A1 RECYCLABLE FILM AND PACKAGING Amcor Flexibles North America, Inc. 2022-07-07 US claimed
EP-3986711-A1 RECYCLABLE FILM AND PACKAGING Amcor Flexibles North America, Inc. (US) 2022-04-27 EP claimed
WO-2020263219-A1 RECYCLABLE FILM AND PACKAGING BEMIS COMPANY, INC. (US) 2020-12-30 WO claimed
EP-2220148-B1 THERMO-SHRINKABLE POLYESTER FILM KOLON INC (KR) 2018-02-07 EP claimed
US-8568841-B2 Thermo-shrinkable polyester film KOLON INDUSTRIES, INC. (KR) 2013-10-29 US claimed
JP-2011507990-A 2011-03-10 JP claimed
US-20100331513-A1 THERMO-SHRINKABLE POLYESTER FILM KOLON INDUSTRIES, INC. (KR) 2010-12-30 US claimed
EP-2220148-A2 THERMO-SHRINKABLE POLYESTER FILM Kolon Industries Inc. (KR) 2010-08-25 EP claimed
WO-2009075533-A2 THERMO-SHRINKABLE POLYESTER FILM KOLON INDUSTRIES, INC. (KR) 2009-06-18 WO claimed
US-20050153131-A1 Load leveling yarns and webbings DURAFIBER TECHNOLOGIES (DFT), INC. (FORMERLY KNOWN AS PERFORMANCE FIBERS, INC.) 2005-07-14 US claimed
US-6310220-B1 Stabilizing polycarbonates CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-30 US claimed
US-20240208191-A1 BIAXIALLY STRETCHED FILM, LAMINATE, AND ECO-FRIENDLY PACKAGING MATERIAL COMPRISING FILM MICROWORKS CO. LTD. (KR) 2024-06-27 US disclosed
EP-3725488-B1 DECORATIVE MOLDED BODY, METHOD FOR PRODUCING SAME AND LIGHT EMITTING STRUCTURE WHICH USES DECORATIVE MOLDED BODY KURARAY CO (JP) 2024-05-22 EP disclosed
EP-4324647-A1 BIAXIALLY STRETCHED FILM, LAMINATE, AND ECO-FRIENDLY PACKAGING MATERIAL COMPRISING FILM SK microworks Co., Ltd. (KR) 2024-02-21 EP disclosed
WO-2023113791-A1 RECYCLABLE PACKAGING FILM WITH DIMENSIONAL STABILITY Amcor Flexibles North America, Inc. (US) 2023-06-22 WO disclosed
EP-1696073-A1 LEATHER-LIKE SHEET MATERIAL AND PROCESS FOR PRODUCING THE SAME Teijin Cordley Limited (JP) 2006-08-30 EP disclosed
EP-1657276-A1 POLYESTER FILM Toyo Boseki Kabushiki Kaisha (JP) 2006-05-17 EP disclosed
US-20040138355-A1 Polyphentlene ether resin composition containing silicon compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2004-07-15 US disclosed
EP-1152079-A1 TWO-WAY WARP KNITTED FABRIC Asahi Kasei Kabushiki Kaisha (JP) 2001-11-07 EP disclosed
US-6310220-B1 Stabilizing polycarbonates CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-30 US disclosed