Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095538 | 0.69 | BRD4 (0.31) | — | |
| SCHEMBL23102106 | 0.66 | QDPR (0.50) | QDPR | |
| SCHEMBL12928634 | 0.60 | TYMP (0.34) | — | |
| SCHEMBL401311 | 0.60 | — | — | |
| SCHEMBL5698236 | 0.58 | ALDH1A1 (0.32) | — | |
| SCHEMBL8091012 | 0.58 | ALDH1A1 (0.32) | — | |
| SCHEMBL296554 | 0.58 | TYMP (0.42) | — | |
| SCHEMBL5698299 | 0.58 | ALDH1A1 (0.32) | — | |
| SCHEMBL7772745 | 0.58 | ALDH1A1 (0.32) | — | |
| SCHEMBL23102114 | 0.58 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708169-A1 | 2,3-DIHYDROBENZO[B][1,4]DIOXINE-6-SULFONAMIDE DERIVATIVES HAVING AN ANTICANCER ACTIVITY | Agios Pharmaceuticals, Inc. (US) | 2020-09-16 | — | — | EP | disclosed |