Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899106 | 0.86 | NPSR1 (0.45) | KMT2AKIF11NPSR1KCNN4 | |
| SCHEMBL2604614 | 0.86 | NPSR1 (0.45) | KMT2AKIF11NPSR1KCNN4 | |
| SCHEMBL993651 | 0.86 | NPSR1 (0.45) | KMT2AKIF11NPSR1KCNN4 | |
| SCHEMBL7718776 | 0.82 | REN (0.42) | CYP1A2CYP2D6MMP3 | |
| SCHEMBL993145 | 0.80 | ALDH1A1 (0.47) | KMT2AKIF11KCNN4CYP2D6 | |
| SCHEMBL346218 | 0.80 | ALDH1A1 (0.47) | KMT2AKIF11KCNN4CYP2D6 | |
| SCHEMBL993439 | 0.80 | ALDH1A1 (0.47) | KMT2AKIF11KCNN4CYP2D6 | |
| SCHEMBL4355319 | 0.80 | HPGDS (0.47) | NPSR1 | |
| SCHEMBL27429530 | 0.79 | PTPN1 (0.41) | MAPT | |
| SCHEMBL28694554 | 0.78 | ALDH1A1 (0.48) | MAPTKMT2AKIF11NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004462-A1 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-05 | — | — | US | claimed |
| US-8093426-B2 | 2-tritylamino-3-(hydroxy or methoxy)propionic acid, or corresponding benzylamide thereof as chemical intermediate; chirally pure lacosamide; high purity | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-10 | — | — | US | disclosed |
| US-20120004452-A1 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-05 | — | — | US | disclosed |
| US-20120004462-A1 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE | RANBAXY LABORATORIES LIMITED (IN) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004452-A1 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE | HDAC2, HDAC5, SCN5A | MAPT 3148/4885KMT2A 178/4885KIF11 1659/4885 |
| US-20120004462-A1 | INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE | HDAC2, HDAC5, SCN5A | MAPT 3148/4885KMT2A 178/4885KIF11 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.