Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 8/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424333 | 0.83 | CLPP (0.54) | PRLHRHDAC6CLPP | |
| SCHEMBL22424705 | 0.81 | MTHFD2 (0.45) | PRLHRMAPK1MTHFD2CLPP | |
| SCHEMBL22424334 | 0.81 | HPGD (0.46) | PRLHRMAPK1MTHFD2CLPP | |
| SCHEMBL22424550 | 0.77 | CLPP (0.53) | PRLHRHDAC6MAPTMEN1ALDH1A1 | |
| SCHEMBL22424557 | 0.77 | MTHFD2 (0.40) | MAPK1HDAC6MTHFD2HTR1AMAPT | |
| SCHEMBL22424217 | 0.76 | CLPP (0.52) | PRLHRHDAC6CLPP | |
| SCHEMBL22424585 | 0.76 | CLPP (0.52) | PRLHRHDAC6CLPP | |
| SCHEMBL22424526 | 0.76 | MTHFD2 (0.42) | PRLHRHDAC6MTHFD2HTR1AMAPT | |
| SCHEMBL22424384 | 0.75 | CLPP (0.51) | PRLHRHDAC6MAPTCLPP | |
| SCHEMBL22424053 | 0.74 | MTHFD2 (0.52) | MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |