Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MTHFD2 | P13995 | 3/20 | 0.46 |
| ▸ | PRLHR | P49683 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24275996 | 0.89 | PRLHR (0.43) | MTHFD2PRLHR | |
| SCHEMBL22424705 | 0.89 | MTHFD2 (0.45) | HPGDMTHFD2PRLHRMAPK1PKM | |
| SCHEMBL22424053 | 0.84 | MTHFD2 (0.52) | HPGDMTHFD2PKM | |
| SCHEMBL24276008 | 0.83 | P2RX7 (0.39) | PRLHRMAPK1 | |
| SCHEMBL22423998 | 0.81 | CLPP (0.60) | HPGDMTHFD2PKMCLPP | |
| SCHEMBL22424504 | 0.81 | PRLHR (0.41) | MTHFD2PRLHRMAPK1CLPP | |
| SCHEMBL22424063 | 0.81 | MTHFD2 (0.50) | HPGDMTHFD2PKMRXFP1 | |
| SCHEMBL22423967 | 0.81 | P2RX7 (0.41) | HPGD | |
| SCHEMBL22424333 | 0.80 | CLPP (0.54) | HPGDPRLHRCLPP | |
| SCHEMBL22410805 | 0.76 | PRLHR (0.41) | HPGDPRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |