Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.50 |
| ▸ | MARK3 | P27448 | 2/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
| ▸ | CLK2 | P49760 | 2/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.50 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.50 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934038 | 0.81 | DYRK3 (0.50) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL1585102 | 0.79 | ADK (0.49) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL16790649 | 0.79 | DYRK3 (0.49) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL23735269 | 0.79 | SRC (0.39) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL11926780 | 0.79 | DYRK3 (0.49) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL23735270 | 0.79 | ADK (0.47) | PRKD3MAP4K4PRKACARPS6KB1CSNK1A1 | |
| SCHEMBL18055946 | 0.79 | DYRK1A (0.39) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL19304152 | 0.75 | SRC (0.57) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL29588876 | 0.75 | SRC (0.57) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 | |
| SCHEMBL3782622 | 0.75 | DYRK3 (0.59) | DYRK3PRKD3MAP4K4PRKACARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280156-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | 深圳华大生命科学研究院 | 2023-01-12 | — | — | WO | disclosed |
| WO-2022083686-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | 深圳华大生命科学研究院 | 2022-04-28 | — | — | WO | disclosed |
| US-11208411-B2 | Compositions and methods for treating parasitic diseases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200291030-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291030-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | LIPA, LSS, LIPC | DYRK3 3682/4885PRKD3 4054/4885MAP4K4 4280/4885 |
| US-11208411-B2 | Compositions and methods for treating parasitic diseases | LIPA, LSS, LIPC | DYRK3 3682/4885PRKD3 4054/4885MAP4K4 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.