⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692957 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL5107250 | 0.80 | — | — | |
| SCHEMBL27941717 | 0.77 | HTR2A (0.46) | — | |
| SCHEMBL5206063 | 0.75 | LPL (0.32) | — | |
| SCHEMBL28180940 | 0.75 | — | — | |
| SCHEMBL16563827 | 0.74 | GAA (0.45) | — | |
| SCHEMBL17198703 | 0.72 | HCAR2 (0.33) | — | |
| SCHEMBL2181931 | 0.71 | ALOX5 (0.38) | — | |
| SCHEMBL128764 | 0.70 | — | — | |
| SCHEMBL9501774 | 0.69 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130380-A1 | PHOSPHONIUM ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. | 2021-05-06 | — | — | US | disclosed |
| US-10968179-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210061763-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2021-03-04 | — | — | US | disclosed |
| US-20200290953-A1 | Charged Ion Channel Blockers and Methods for Use | Nocion Therapeutics, Inc. | 2020-09-17 | — | — | US | disclosed |
| CN-101835781-B | Herbicide | SYNGENTA LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101835781-A | Novel herbicide | SYNGENTA LTD | 2010-09-15 | — | — | CN | disclosed |