SCHEMBL22432065

SCHEMBL22432065

Cc1cc(-c2cccc3c2oc2ccccc23)ccc1N(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccc(-c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
GGPS1 O95749 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.36
PRKDC P78527 1/20 0.36
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 4/20 0.35
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA1 P02708 1/20 0.34
CHRNG P07510 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22432004 0.98 ALOX5 (0.43) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL22431995 0.98 ALOX5 (0.43) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL22547061 0.97 ALOX5 (0.45) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL22432000 0.96 ALOX5 (0.43) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL22432074 0.95 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL21085270 0.95 ALOX5 (0.50) ALOX5GGPS1PTGES2PRKDCALDH1A1
SCHEMBL22431998 0.91 ALOX5 (0.46) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL24748101 0.88 ALOX5 (0.48) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL24748096 0.88 ALOX5 (0.48) ALOX5GGPS1PTGES2PRKDCENPP3
SCHEMBL23238322 0.88 ALOX5 (0.48) ALOX5GGPS1PTGES2PRKDCENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159479-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-05-25 US disclosed
US-20230159479-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-05-25 US disclosed
EP-3939970-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd. (JP) 2022-01-19 EP disclosed
US-20200290985-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159479-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, RER1, OR10J3 ALOX5 3071/4885GGPS1 2593/4885PTGES2 3720/4885
US-20200290985-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, RER1, OR10J3 ALOX5 3071/4885GGPS1 2593/4885PTGES2 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.