SCHEMBL20636166

SCHEMBL20636166

CC(C)c1cccc(C(C)C)c1NC(=O)NS(=O)(=O)C1CCN(CC(F)(F)F)CC1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20635801 0.95 MEN1 (0.46) MEN1KMT2ATDP1
SCHEMBL22433298 0.89 — —
SCHEMBL22433562 0.89 MEN1 (0.49) MEN1KMT2ATDP1
SCHEMBL24922841 0.89 KAT6A (0.39) —
SCHEMBL20636162 0.88 NLRP3 (0.46) —
SCHEMBL22433573 0.87 — —
SCHEMBL20635082 0.85 MEN1 (0.43) MEN1KMT2ATDP1
SCHEMBL22433383 0.85 — —
SCHEMBL20634279 0.85 MEN1 (0.48) MEN1KMT2ATDP1
SCHEMBL20634273 0.84 NLRP3 (0.46) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2023-02-02 — — US disclosed
WO-2019008025-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2019-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 MEN1 4122/4885KMT2A 2774/4885TDP1 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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