Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | OGA | O60502 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412680 | 0.82 | OGA (0.61) | OGA | |
| SCHEMBL21370127 | 0.80 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2OGAALDH1A1HTT | |
| SCHEMBL25625991 | 0.78 | ALDH1A1 (0.56) | LMNAGAASMN1; SMN2OGAALDH1A1 | |
| SCHEMBL21369461 | 0.78 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2OGAALDH1A1HTT | |
| SCHEMBL21370130 | 0.78 | ALDH1A1 (0.67) | LMNASMN1; SMN2OGAALDH1A1HTT | |
| SCHEMBL22079383 | 0.77 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2OGAALDH1A1HTT | |
| SCHEMBL22079257 | 0.77 | SMN1; SMN2 (0.51) | LMNAGAASMN1; SMN2OGAALDH1A1 | |
| SCHEMBL22079715 | 0.76 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2OGAALDH1A1HTT | |
| SCHEMBL22433770 | 0.73 | OGA (0.45) | LMNAGAASMN1; SMN2OGA | |
| SCHEMBL16113387 | 0.72 | OGA (0.71) | LMNASMN1; SMN2OGAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185593-A1 | AZETIDINYL 0-GLYC0PR0TEIN-2-ACETAMID0-2-DEOXY-3-D-GLUC0PYRAN0SIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-09-17 | — | — | WO | disclosed |