Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434601 | 1.00 | CTSK (0.52) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL32665409 | 0.92 | ME3 (0.54) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL3708015 | 0.90 | CTSK (0.52) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL31142639 | 0.89 | EPHX2 (0.44) | CTSKPIM1PIM3PIM2CKS1B | |
| SCHEMBL31142648 | 0.89 | EPHX2 (0.44) | CTSKPIM1PIM3PIM2CKS1B | |
| SCHEMBL12841264 | 0.89 | SUV39H2 (0.52) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL16434657 | 0.89 | KDM4D (0.52) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL30936771 | 0.89 | CTSK (0.51) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL16544562 | 0.89 | KDM4D (0.52) | CTSKPIM1PIM3PIM2SUV39H2 | |
| SCHEMBL1413310 | 0.89 | KDM4D (0.52) | CTSKPIM1PIM3PIM2SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-20200291020-A1 | NEW [1,6]NAPHTHYRIDINE COMPOUNDS AND DERIVATIVES AS CDK8/CDK19 INHIBITORS | BOEHRINGER INGELHEIM RCV GMBH & CO. KG (AT) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291020-A1 | NEW [1,6]NAPHTHYRIDINE COMPOUNDS AND DERIVATIVES AS CDK8/CDK19 INHIBITORS | CDK9, CDK19, CDK8 | CTSK 2225/4885PIM1 455/4885PIM3 699/4885 |
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CTSK 4297/4885PIM1 3331/4885PIM3 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.