SCHEMBL22436615

SCHEMBL22436615

C=C(C)C(=O)[SiH](OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
ALDH1A1 P00352 5/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TSHR P16473 4/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377628 0.82 TSHR (0.38) THRBALDH1A1TSHR
SCHEMBL29376873 0.72 ALDH1A1 (0.43) ALDH1A1HSD17B10TSHRTDP1
SCHEMBL28618492 0.71 ALDH1A1 (0.31) ALDH1A1TSHR
Methacrylic Acid SCHEMBL1419612 0.71 THRB (0.38) THRBALDH1A1LMNAHSD17B10MGAM
SCHEMBL27655903 0.70 ALDH1A1 (0.37) THRBALDH1A1LMNAHSD17B10MGAM
SCHEMBL28606229 0.68 THRB (0.44) THRBALDH1A1LMNAHSD17B10MGAM
SCHEMBL1270674 0.67
SCHEMBL28054012 0.67
SCHEMBL27951728 0.67
SCHEMBL2139228 0.67 SOAT1 (0.38) ALDH1A1LMNAHSD17B10MGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112279665-B Wave-absorbing ceramic precursor and preparation method and application thereof 浙江华茂航天科技股份有限公司 2022-06-07 CN disclosed
CN-112126067-B Preparation method and application of liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-04-05 CN disclosed
CN-112126064-B Preparation method of solid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-04-05 CN disclosed
CN-112280048-B Preparation method of polyborocarbosilane 浙江华茂航天科技股份有限公司 2022-02-18 CN disclosed
CN-112266482-B Polyaluminocarbosilane and preparation method thereof 浙江华茂航天科技股份有限公司 2022-02-18 CN disclosed
CN-112142984-B Polyaluminocarbosilane and preparation method and application thereof 浙江华茂航天科技股份有限公司 2022-02-08 CN disclosed
EP-3710414-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed