Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.47 |
| ▸ | CES2 | O00748 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099851 | 0.84 | CES2 (0.54) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL828942 | 0.82 | HDAC3 (0.44) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL26929048 | 0.78 | CES2 (0.46) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL28770109 | 0.77 | CES1 (0.46) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL2106681 | 0.76 | ALDH1A1 (0.44) | CES1CES2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL238059 | 0.75 | CES1 (0.44) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL17497122 | 0.75 | HDAC3 (0.41) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL29096111 | 0.74 | CES2 (0.45) | CES1CES2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL1524419 | 0.74 | CES2 (0.46) | CES1CES2HDAC3HDAC4HDAC1 | |
| SCHEMBL11568029 | 0.72 | HDAC1 (0.42) | CES1CES2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710061-A1 | POLYMER PRODRUGS AND SUBCUTANEOUS AND/OR INTRAMUSCULAR ADMINISTRATION THEREOF | Centre National de la Recherche Scientifique (FR) | 2020-09-23 | — | — | EP | disclosed |