SCHEMBL28770109

SCHEMBL28770109

O=C(O)SC(=S)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.46
CES2 O00748 4/20 0.46
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
TDP1 Q9NUW8 4/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
HSD17B10 Q99714 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA9 Q16790 2/20 0.42
POLB P06746 1/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2106681 0.85 ALDH1A1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL238059 0.84 CES1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL26929048 0.82 CES2 (0.46) CES1CES2ALDH1A1TSHRDAO
SCHEMBL1524419 0.82 CES2 (0.46) CES1CES2ALDH1A1TSHRDAO
SCHEMBL828942 0.79 HDAC3 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL22438596 0.77 CES1 (0.47) CES1CES2ALDH1A1TDP1CYP3A4
SCHEMBL176121 0.74 ALDH1A1 (0.44) CES1CES2ALDH1A1TSHRDAO
SCHEMBL7865764 0.73 AKR1C3 (0.43) CES1CES2ALDH1A1TSHRDAO
SCHEMBL164078 0.73 CES1 (0.42) CES1CES2ALDH1A1TSHRDAO
SCHEMBL36053 0.71 CES1 (0.46) CES1CES2ALDH1A1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167982-A The manufacturing method of block copolymer and block copolymer 电化株式会社 2019-08-23 CN disclosed
CN-108473904-A Nitrogen functionalized olefin polymers for engine lubricants 路博润公司 2018-08-31 CN disclosed
CN-103358749-B Original edition of lithographic printing plate 富士胶片株式会社 2018-01-30 CN disclosed
CN-102942981-B Prepare the method for polymkeric substance and composition thereof LUBRIZOL CORP. (US) 2016-02-10 CN disclosed
CN-104704014-A Loose core star polymers and lubricating compositions thereof LUBRIZOL CORP 2015-06-10 CN disclosed
CN-103189483-B Star polymers and lubricating compositions thereof LUBRIZOL CORP 2014-11-26 CN disclosed
CN-103358749-A Lithographic printing plate precursor FUJIFILM CORP 2013-10-23 CN disclosed
CN-103189483-A Star polymers and lubricating compositions thereof LUBRIZOL CORP 2013-07-03 CN disclosed
CN-101087812-B Process for preparing polymers and compositions thereof LUBRIZOL CORP 2013-03-06 CN disclosed
CN-102942981-A Process for preparing polymers and compositions thereof LUBRIZOL CORP 2013-02-27 CN disclosed
CN-101087812-A Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2007-12-12 CN disclosed