Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043639 | 0.87 | CPT2 (0.57) | MEN1KMT2AMAPTPTPN7TDP1 | |
| SCHEMBL22406920 | 0.84 | PARG (0.47) | PARGMEN1KMT2AL3MBTL1PARP1 | |
| SCHEMBL22439711 | 0.84 | KMO (0.55) | KDM4EKMOSCN9AALDH1A1POLB | |
| SCHEMBL22407065 | 0.83 | PARG (0.51) | PARGMEN1KMT2AL3MBTL1PARP1 | |
| SCHEMBL29377336 | 0.83 | TSHR (0.46) | MAPTKMORAB9AMAOAMAOB | |
| SCHEMBL22406867 | 0.83 | TSHR (0.46) | MAPTKMORAB9AMAOAMAOB | |
| SCHEMBL22439740 | 0.82 | KMO (0.50) | KMT2AMAPTKDM4EKMONPC1 | |
| SCHEMBL22439730 | 0.80 | PPARA (0.45) | KMOSCN9A | |
| SCHEMBL22439750 | 0.79 | PPARG (0.44) | KMOSCN9A | |
| SCHEMBL22439712 | 0.79 | SCN9A (0.44) | MAPTKMORAB9ASCN9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712135-A1 | AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE | Kureha Corporation (JP) | 2020-09-23 | — | — | EP | disclosed |