SCHEMBL22406867

SCHEMBL22406867

O=C(O)C(=O)c1ccc(Oc2ccc(Cl)cc2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
CASP1 P29466 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KMO O15229 1/20 0.43
XDH P47989 1/20 0.43
SLC22A12 Q96S37 1/20 0.43
CDH1 P12830 1/20 0.42
CTNNB1 P35222 1/20 0.42
TCF7L2 Q9NQB0 1/20 0.42
STK39 Q9UEW8 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
ERCC5 P28715 2/20 0.41
FEN1 P39748 2/20 0.41
CHEK2 O96017 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377336 1.00 TSHR (0.46) TSHRCASP1SMN1; SMN2KMOXDH
SCHEMBL22439711 0.88 KMO (0.55) TSHRCASP1SMN1; SMN2KMOCHEK2
SCHEMBL22439730 0.87 PPARA (0.45) KMOXDHPPARGPPARA
SCHEMBL22439723 0.87 ALDH1A1 (0.46) KMOXDHSLC22A12CDH1CTNNB1
SCHEMBL28521601 0.86 TSHR (0.63) TSHRCASP1SMN1; SMN2KMOXDH
SCHEMBL22439740 0.86 KMO (0.50) TSHRCASP1SMN1; SMN2KMOXDH
SCHEMBL22439712 0.86 SCN9A (0.44) TSHRCASP1SMN1; SMN2KMOSTK39
SCHEMBL22439738 0.84 XDH (0.41) XDHSLC22A12CDH1CTNNB1TCF7L2
SCHEMBL22439721 0.84 CYP11B1 (0.48) XDHSLC22A12CDH1CTNNB1TCF7L2
SCHEMBL22439737 0.83 PARG (0.47) KMOSTK39MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12207654-B2 Bactericidal agent for agricultural or horticultural use, plant disease control method, and product for plant disease control use KUREHA CORPORATION (JP) 2025-01-28 US disclosed
EP-3957177-B1 FUNGICIDAL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE, PLANT DISEASE CONTROL METHOD, AND PRODUCT FOR PLANT DISEASE CONTROL USE KUREHA CORP (JP) 2024-04-03 EP disclosed
EP-3712135-B1 AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE KUREHA CORP (JP) 2023-05-03 EP disclosed
US-20220217978-A1 BACTERICIDAL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE, PLANT DISEASE CONTROL METHOD, AND PRODUCT FOR PLANT DISEASE CONTROL USE KUREHA CORPORATION (JP) 2022-07-14 US disclosed
EP-3957177-A1 BACTERICIDAL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE, PLANT DISEASE CONTROL METHOD, AND PRODUCT FOR PLANT DISEASE CONTROL USE Kureha Corporation (JP) 2022-02-23 EP disclosed
US-10945434-B2 Azole derivative, intermediate compound, method for producing azole derivative, agricultural or horticultural chemical agent, and protective agent for industrial material KUREHA CORPORATION (JP) 2021-03-16 US disclosed
EP-3712135-A1 AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE Kureha Corporation (JP) 2020-09-23 EP disclosed
US-20200288714-A1 AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL CHEMICAL AGENT, AND PROTECTIVE AGENT FOR INDUSTRIAL MATERIAL KUREHA CORPORATION (JP) 2020-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12207654-B2 Bactericidal agent for agricultural or horticultural use, plant disease control method, and product for plant disease control use BROX, MGAM, CYP51A1 TSHR 3139/4885CASP1 8/4885SMN1; SMN2 4316/4885
US-10945434-B2 Azole derivative, intermediate compound, method for producing azole derivative, agricultural or horticultural chemical agent, and protective agent for industrial material NOS2, NOS1, CYP51A1 TSHR 4125/4885CASP1 506/4885SMN1; SMN2 3032/4885
US-20200288714-A1 AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGRICULTURAL OR HORTICULTURAL CHEMICAL AGENT, AND PROTECTIVE AGENT FOR INDUSTRIAL MATERIAL NOS2, NOS1, CYP51A1 TSHR 4125/4885CASP1 506/4885SMN1; SMN2 3032/4885
US-20220217978-A1 BACTERICIDAL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE, PLANT DISEASE CONTROL METHOD, AND PRODUCT FOR PLANT DISEASE CONTROL USE BROX, MGAM, CYP51A1 TSHR 3139/4885CASP1 8/4885SMN1; SMN2 4316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.