⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015353 | 0.77 | — | — | |
| SCHEMBL2243487 | 0.77 | — | — | |
| SCHEMBL8992653 | 0.76 | — | — | |
| SCHEMBL9120551 | 0.74 | OPRM1 (0.30) | — | |
| SCHEMBL4818735 | 0.72 | — | — | |
| SCHEMBL15062415 | 0.70 | — | — | |
| SCHEMBL25179795 | 0.67 | — | — | |
| SCHEMBL64120 | 0.65 | LMNA (0.30) | — | |
| SCHEMBL430757 | 0.65 | — | — | |
| SCHEMBL4194682 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367855-B2 | Process for preparing silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2013-02-05 | — | — | US | disclosed |
| EP-2361916-B1 | Method for manufacturing silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2361916-A1 | Method for manufacturing silylorganoamines | Evonik Degussa GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2361917-A1 | Method for manufacturing silylorganoamines | Evonik Degussa GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| US-20110201835-A1 | Process for Preparing Silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-0531948-B1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5393353-A | Immersion of alloy surface in phosphorous acid selected from phosphoric, phosphorous or hypophosphoric acid and mixture containing atleast one silane compound; removal, drying | MCGEAN-ROHCO, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0531948-A1 | Process for preparation of bis- and tris(silylorgano)-amines | DOW CORNING CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5101055-A | From the corresponding mono- and di-compounds, palladium monoxide catalyst | DOW CORNING CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |