Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197211 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| SCHEMBL1196173 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| SCHEMBL387177 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| Boric Acid SCHEMBL30679497 | 0.91 | ALDH1A1 (0.38) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| Boric Acid SCHEMBL30679498 | 0.91 | ALDH1A1 (0.38) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| Isopropyl Alcohol SCHEMBL19951528 | 0.89 | ALDH1A1 (0.36) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| Isopropyl Alcohol SCHEMBL19951527 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| SCHEMBL30791101 | 0.87 | ACLY (0.54) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| SCHEMBL11418482 | 0.85 | TSHR (0.45) | ALDH1A1TSHRACLYFFAR3MEN1 | |
| SCHEMBL28448094 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRACLYFFAR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299306-A1 | COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF | UNIVERSITA' DI PISA (IT) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299306-A1 | COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF | MKI67, CCNI, CASP3 | ALDH1A1 149/4885TSHR 2723/4885ACLY 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.