SCHEMBL2244293

SCHEMBL2244293

C=CCCC[Si](CC)(OCCCC)OCCCC

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2244279 0.91 TSHR (0.43) TSHRALDH1A1
SCHEMBL2240911 0.82 TSHR (0.41) TSHRALDH1A1
SCHEMBL707072 0.82 ADRB2 (0.36) TSHRALDH1A1
SCHEMBL703938 0.82 ADRB2 (0.36) TSHRALDH1A1
SCHEMBL5833984 0.82 ADRB2 (0.36) TSHRALDH1A1
SCHEMBL1270316 0.81 TSHR (0.50) TSHRALDH1A1HPGDATM
SCHEMBL707587 0.80 ADRB2 (0.38) TSHRALDH1A1ATM
SCHEMBL2241355 0.79 TSHR (0.48) TSHRALDH1A1HPGDATM
SCHEMBL5833540 0.78 ADRB2 (0.36) TSHRALDH1A1
SCHEMBL2861945 0.76 DNM1 (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
EP-1837360-A1 VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME Konishi Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070117902-A1 Vinyl-urethane copolymers and production methods thereof KONISHI CO., LTD. (JP) 2007-05-24 US disclosed