SCHEMBL22443293

SCHEMBL22443293

CCOC(=O)c1[nH]c2ccccc2c1-c1cc2ccccc2[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.54
HTR6 P50406 2/20 0.54
TUBB4A P04350 2/20 0.53
TUBB P07437 2/20 0.53
TUBA3C P0DPH7 2/20 0.53
TUBA1B P68363 2/20 0.53
TUBA4A P68366 2/20 0.53
TUBB4B P68371 2/20 0.53
TUBB3 Q13509 2/20 0.53
TUBB2A Q13885 2/20 0.53
TUBB8 Q3ZCM7 2/20 0.53
TUBA3E Q6PEY2 2/20 0.53
TUBA1A Q71U36 2/20 0.53
TUBA1C Q9BQE3 2/20 0.53
TUBB6 Q9BUF5 2/20 0.53
TUBB2B Q9BVA1 2/20 0.53
TUBB1 Q9H4B7 2/20 0.53
ALDH1A1 P00352 5/20 0.53
HPGD P15428 4/20 0.53
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24487452 0.86 TUBB4A (0.50) KDM4ETUBB4ATUBBTUBA3CTUBA1B
SCHEMBL2956667 0.80 ALDH1A1 (0.73) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL8728734 0.80 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL2809045 0.79 MAPT (0.54) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL2205697 0.78 KDM4E (0.57) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL24487443 0.78 HTR6 (0.61) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL7679887 0.78 MAPT (0.60) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL14158280 0.77 KDM4E (0.55) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL2880010 0.77 KDM4E (0.66) KDM4EHTR6TUBB4ATUBBTUBA3C
SCHEMBL24487442 0.76 KDM4E (0.55) KDM4EHTR6TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941920-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-03-20 EP disclosed
US-20220177478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK KGAA (DE) 2022-06-09 US disclosed
EP-3941920-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2022-01-26 EP disclosed
WO-2020187865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-24 WO disclosed
WO-2020187865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM KDM4E 1889/4885HTR6 2197/4885TUBB4A 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.