Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443270 | 0.86 | MAPT (0.46) | MAPTALDH1A1MEN1USP2HTT | |
| SCHEMBL22443269 | 0.86 | MAPT (0.46) | MAPTALDH1A1MEN1USP2HTT | |
| SCHEMBL1071568 | 0.83 | MEN1 (0.59) | MAPTMEN1USP2HTTRECQL | |
| SCHEMBL597411 | 0.83 | MEN1 (0.59) | MAPTMEN1USP2HTTRECQL | |
| Hydrochloric Acid SCHEMBL29936057 | 0.82 | MEN1 (0.58) | MAPTMEN1USP2HTTRECQL | |
| SCHEMBL7858944 | 0.78 | MAPT (0.42) | MAPTALDH1A1MEN1USP2HTT | |
| SCHEMBL29359698 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL6671231 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL6159827 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL5323052 | 0.74 | GSTM2 (0.61) | MEN1USP2HTTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941582-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | The University Court Of The University Of Edinburgh (GB) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187913-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-09-24 | — | — | WO | disclosed |