SCHEMBL1071568

SCHEMBL1071568

N[C@@H](CNc1ccc([N+](=O)[O-])c2nonc12)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.59
▸ KMT2A Q03164 8/20 0.59
▸ USP2 O75604 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ RECQL P46063 1/20 0.59
▸ GSTM2 P28161 1/20 0.57
▸ MYC P01106 9/20 0.54
▸ MAX P61244 5/20 0.54
▸ IDO1 P14902 3/20 0.53
▸ MIF P14174 1/20 0.53
▸ POLB P06746 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ HRH3 Q9Y5N1 2/20 0.48
▸ PSMD14 O00487 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597411 1.00 MEN1 (0.59) MEN1KMT2AUSP2HTTRECQL
Hydrochloric Acid SCHEMBL29936057 0.99 MEN1 (0.58) MEN1KMT2AUSP2HTTRECQL
SCHEMBL5323052 0.91 GSTM2 (0.61) MEN1KMT2AUSP2HTTRECQL
SCHEMBL22443336 0.83 MAPT (0.42) MEN1KMT2AUSP2HTTRECQL
SCHEMBL10824789 0.81 MEN1 (0.66) MEN1KMT2AUSP2HTTRECQL
SCHEMBL7858944 0.80 MAPT (0.42) MEN1KMT2AUSP2HTTRECQL
SCHEMBL17525024 0.79 GSTM2 (0.67) MEN1KMT2AUSP2HTTRECQL
SCHEMBL13589830 0.77 GSTM2 (0.62) MEN1KMT2AUSP2HTTRECQL
SCHEMBL8427049 0.77 GSTM2 (0.81) MEN1KMT2AUSP2HTTRECQL
SCHEMBL8429536 0.77 GSTM2 (0.68) MEN1KMT2AUSP2HTTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170370916-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-12-28 — — US disclosed
US-20170370916-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-12-28 — — US disclosed
US-20150369800-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-12-24 — — US disclosed
US-20150369800-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-12-24 — — US disclosed
US-20150369800-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-12-24 — — US disclosed
US-8940506-B2 High-sensitive fluorescent energy transfer assay using fluoresent amino acids and fluorescent proteins THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-01-27 — — US disclosed
US-8940506-B2 High-sensitive fluorescent energy transfer assay using fluoresent amino acids and fluorescent proteins THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-01-27 — — US disclosed
US-20110117556-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-05-19 — — US disclosed
US-20110117556-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-05-19 — — US disclosed
EP-2271662-A2 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS The Regents Of The University Of California (US) 2011-01-12 — — EP disclosed
WO-2009117726-A2 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-09-24 — — WO disclosed
WO-2009117726-A2 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-09-24 — — WO disclosed
US-20090081669-A1 Fluorescent Assays Using Orthogonal tRNA - Aminoacyl Synthetase Pairs ENCODE BIO, INC. (US) 2009-03-26 — — US disclosed
WO-2007090198-A2 FLUORESCENT ASSAYS USING ORTHOGONAL TRNA - AMINOACYL SYNTHETASE PAIRS ENCODE BIO, INC. (US) 2007-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117556-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS SLC7A1, SARS1, GFPT1 MEN1 3695/4885KMT2A 3456/4885USP2 2955/4885
US-20150369800-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS GFPT1, PHAX, TARBP1 MEN1 3636/4885KMT2A 3484/4885USP2 3015/4885
US-20170370916-A1 HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS ACP1, BCAT1, SARS1 MEN1 3513/4885KMT2A 3471/4885USP2 2739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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