SCHEMBL22443390

SCHEMBL22443390

CC1(C)CC(C(=O)O)N1Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRM6 O15303 1/20 0.51
AMPD2 Q01433 4/20 0.46
ACE P12821 1/20 0.43
S1PR1 P21453 1/20 0.43
S1PR5 Q9H228 1/20 0.43
GRM2 Q14416 1/20 0.43
GAA P10253 1/20 0.42
ELANE P08246 1/20 0.42
OPRK1 P41145 1/20 0.42
ALDH1A1 P00352 2/20 0.42
AGTR2 P50052 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD11B1 P28845 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5451611 0.84 GRM6 (0.52) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL5550768 0.84 GRM6 (0.52) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL24832496 0.81 GRM6 (0.47) GRM6ACES1PR1S1PR5GRM2
SCHEMBL22443525 0.76 SIGMAR1 (0.45) AMPD2GAAELANEOPRK1TSHR
SCHEMBL6128166 0.74 GRM6 (0.49) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL5965414 0.74 GRM6 (0.49) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL5965412 0.74 GRM6 (0.49) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL6647307 0.73 GRM6 (0.48) GRM6AMPD2ACES1PR1S1PR5
SCHEMBL21245089 0.72 AMPD2 (0.48) GRM6AMPD2GAAELANEALDH1A1
SCHEMBL4710674 0.72 GRM6 (0.49) GRM6ACES1PR1S1PR5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378216-B2 Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia ATROGI AB (SE) 2025-08-05 US disclosed
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed
US-20220194920-A1 HETEROARYL(HETEROCYCLYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2022-06-23 US disclosed
US-20220194920-A1 HETEROARYL(HETEROCYCLYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2022-06-23 US disclosed
US-20220152004-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2022-05-19 US disclosed
US-20220152004-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2022-05-19 US disclosed
EP-3941913-A1 HETEROARYL(HETEROCYCLYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2022-01-26 EP disclosed
EP-3941468-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2022-01-26 EP disclosed
CN-113784961-A Heteroaryl (heterocyclyl) carbinol compounds useful for treating hyperglycemia 阿托基公司 2021-12-10 CN disclosed
CN-113784953-A Heterocyclyl (phenyl) carbinol compounds useful for treating hyperglycemia 阿托基公司 2021-12-10 CN disclosed
WO-2020188301-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2020-09-24 WO disclosed
WO-2020188301-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2020-09-24 WO disclosed
WO-2020188299-A1 HETEROARYL(HETEROCYCLYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2020-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220152004-A1 HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA GPR119, SLC5A1, SLC5A2 GRM6 3895/4885AMPD2 1219/4885ACE 492/4885
US-12378216-B2 Heteroaryl(heterocyclyl)methanol compounds useful in the treatment of hyperglycaemia SLC5A1, GPR119, SLC5A2 GRM6 3054/4885AMPD2 2232/4885ACE 554/4885
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD GRM6 3390/4885AMPD2 3549/4885ACE 1/4885
US-20220194920-A1 HETEROARYL(HETEROCYCLYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA SLC5A1, GPR119, SLC5A2 GRM6 3054/4885AMPD2 2232/4885ACE 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.