Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26008195 | 1.00 | TBXAS1 (0.51) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL26009175 | 0.88 | LMNA (0.47) | TBXAS1LMNANAPRTCYP1A2CYP3A4 | |
| SCHEMBL29794529 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL30937414 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL29794532 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL31370303 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL6220905 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL14640282 | 0.85 | TBXAS1 (0.57) | TBXAS1GPR132LMNAKDM4ENAPRT | |
| SCHEMBL164831 | 0.82 | MME (0.58) | KMT2A | |
| SCHEMBL12683553 | 0.82 | MME (0.58) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |