Sugi Predict

Sugi Predict / Compounds / SCHEMBL14640282

SCHEMBL14640282

SCHEMBL14640282

CNC(Cc1cccnc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TBXAS1 P24557 3/20 0.57
▸ KDM4E B2RXH2 1/20 0.53
▸ NAPRT Q6XQN6 1/20 0.51
▸ GPR132 Q9UNW8 5/20 0.51
▸ FDPS P14324 1/20 0.50
▸ CMKLR2 P46091 1/20 0.48
▸ CMKLR1 Q99788 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ FOLH1 Q04609 1/20 0.47
▸ ECE1 P42892 1/20 0.47
▸ LMNA P02545 2/20 0.47
▸ RECQL P46063 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CHRM1 P11229 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ HPGD P15428 1/20 0.46
▸ HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29794532 1.00 TBXAS1 (0.57) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL6220905 1.00 TBXAS1 (0.57) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL29794529 1.00 TBXAS1 (0.57) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL30937414 1.00 TBXAS1 (0.57) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL31370303 1.00 TBXAS1 (0.57) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL12220088 0.88 TBXAS1 (0.50) TBXAS1KDM4ENAPRTFDPSPKM
SCHEMBL13934329 0.88 TBXAS1 (0.50) TBXAS1KDM4ENAPRTFDPSPKM
SCHEMBL14898388 0.88 TBXAS1 (0.50) TBXAS1KDM4ENAPRTFDPSPKM
SCHEMBL23093209 0.85 NLRP3 (0.56) TBXAS1KDM4ENAPRTGPR132FDPS
SCHEMBL3781118 0.85 GPR132 (0.55) TBXAS1KDM4ENAPRTGPR132FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 — — US claimed
US-12637494-B2 Method for producing peptide containing non-natural amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-26 — — US disclosed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 — — WO disclosed
EP-4594336-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PeptiDream Inc. (JP) 2025-08-06 — — EP disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 — — WO disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 — — WO disclosed
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 — — US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 — — US disclosed
US-20230069218-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-02 — — US disclosed
CN-115667539-A Translation system with altered genetic code tables 中外制药株式会社 2023-01-31 — — CN disclosed
EP-4074829-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-10-19 — — EP disclosed
CN-114787359-A Method for producing peptide containing unnatural amino acid 中外制药株式会社 2022-07-22 — — CN disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 — — US disclosed
EP-3939962-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-01-19 — — EP disclosed
WO-2021261577-A1 TRANSLATION SYSTEM PROVIDED WITH MODIFIED GENETIC CODE TABLE 中外製薬株式会社 2021-12-30 — — WO disclosed
WO-2021117848-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID 中外製薬株式会社 2021-06-17 — — WO disclosed
WO-2021117848-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID 中外製薬株式会社 2021-06-17 — — WO disclosed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637494-B2 Method for producing peptide containing non-natural amino acid MRPL21, RPL21, RPL30 TBXAS1 2605/4885KDM4E 1686/4885NAPRT 2332/4885
US-20230069218-A1 METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID MRPL21, RPL41, RPL21 TBXAS1 3660/4885KDM4E 3633/4885NAPRT 2855/4885
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR TBXAS1 3606/4885KDM4E 626/4885NAPRT 2582/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR TBXAS1 3606/4885KDM4E 626/4885NAPRT 2582/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR TBXAS1 3606/4885KDM4E 626/4885NAPRT 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.