Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 16/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22447646 | 0.93 | TNF (0.67) | TNFLMNAMCL1 | |
| SCHEMBL24542779 | 0.86 | MCL1 (0.57) | TNFLMNAMCL1 | |
| SCHEMBL12963735 | 0.79 | LMNA (0.61) | TNFLMNAMCL1 | |
| SCHEMBL22447405 | 0.79 | MCL1 (0.62) | TNFLMNAMCL1 | |
| SCHEMBL15205271 | 0.78 | TNF (0.52) | TNFLMNAMCL1 | |
| SCHEMBL22447643 | 0.77 | MCL1 (0.57) | TNFLMNAMCL1 | |
| SCHEMBL17537381 | 0.77 | TNF (0.66) | TNFLMNA | |
| SCHEMBL20786919 | 0.77 | LMNA (0.65) | TNFLMNAMCL1 | |
| SCHEMBL13717683 | 0.77 | MCL1 (0.58) | TNFLMNAMCL1 | |
| SCHEMBL4210572 | 0.76 | MCL1 (0.61) | TNFLMNAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |