SCHEMBL17537381

SCHEMBL17537381

CCOC(=O)CCCn1cnc2cc3ncn(CCCC(=O)OCC)c3cc21

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TNF P01375 14/20 0.66
LMNA P02545 2/20 0.55
MAPT P10636 3/20 0.48
ALDH1A1 P00352 2/20 0.48
POLB P06746 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 1/20 0.46
HTT P42858 1/20 0.46
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21131550 0.92 TNF (0.57) TNFLMNAMAPTALDH1A1POLB
SCHEMBL5884818 0.84 TDP1 (0.61) TNFLMNAMAPTALDH1A1MEN1
SCHEMBL10468105 0.81 TNF (0.54) TNFMEN1KMT2AABL1RIN1
SCHEMBL10467934 0.81 TNF (0.54) TNFMEN1KMT2AABL1RIN1
SCHEMBL15323671 0.77 TNF (0.53) TNFMAPTALDH1A1POLBMEN1
SCHEMBL15323299 0.77 TNF (0.53) TNFMAPTALDH1A1POLBMEN1
SCHEMBL10468203 0.77 TNF (0.53) TNFMEN1KMT2AABL1RIN1
SCHEMBL10467879 0.77 TNF (0.53) TNFMEN1KMT2AABL1RIN1
SCHEMBL22447404 0.77 TNF (0.77) TNFLMNA
SCHEMBL10469111 0.76 TNF (0.55) TNFLMNAMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
US-20200371062-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2020-11-26 US disclosed
US-10761053-B2 Non-enzymatic electrochemical sensor for measuring analytes TERUMO KABUSHIKI KAISHA (JP) 2020-09-01 US disclosed
EP-3134419-B1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO CORP (JP) 2019-03-13 EP disclosed
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2017-08-03 US disclosed
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2017-08-03 US disclosed
WO-2015164578-A9 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES GLUCOVATION, INC. (US) 2016-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, SRR, BLVRB TNF 4574/4885LMNA 2494/4885MAPT 4808/4885
US-20200371062-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES XDH, SPR, BLVRB TNF 3977/4885LMNA 1619/4885MAPT 4832/4885
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, BLVRB, XDH TNF 3918/4885LMNA 1709/4885MAPT 4842/4885
US-10761053-B2 Non-enzymatic electrochemical sensor for measuring analytes XDH, SPR, BLVRB TNF 3960/4885LMNA 1491/4885MAPT 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.