Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749845 | 0.79 | GABRA1 (0.39) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL15614474 | 0.76 | GABRA1 (0.37) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL25613928 | 0.76 | GABRA1 (0.37) | GABRA1GABRB1CA1CA2 | |
| SCHEMBL12197721 | 0.76 | SLC6A2 (0.48) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL22448790 | 0.75 | LMNA (0.44) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL22448704 | 0.74 | LMNA (0.42) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL22448616 | 0.74 | POLB (0.36) | GABRA1GABRB1KMT2A | |
| SCHEMBL25927987 | 0.74 | GABRA1 (0.35) | GABRA1GABRB1LMNA | |
| SCHEMBL23510746 | 0.74 | LMNA (0.42) | GABRA1GABRB1LMNASLC6A2HTR2B | |
| SCHEMBL16248167 | 0.74 | LMNA (0.48) | GABRA1GABRB1LMNASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964505-A1 | SOLID FORM OF DIAMINOPYRIMIDINE COMPOUND OR HYDRATE THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| EP-3712144-A1 | P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |