Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448793 | 0.83 | POLB (0.36) | POLBALDH1A1GAAALOX15HTT | |
| SCHEMBL22448669 | 0.78 | JAK2 (0.34) | POLBALDH1A1GAAALOX15HTT | |
| SCHEMBL22448805 | 0.77 | POLB (0.32) | POLBALDH1A1GAAALOX15HTT | |
| SCHEMBL5529615 | 0.76 | LMNA (0.45) | POLBALDH1A1GAAGABRA1GABRB1 | |
| SCHEMBL22448705 | 0.75 | POLB (0.46) | POLBGAAP2RX3P2RX2 | |
| SCHEMBL1494087 | 0.75 | P2RX3 (0.47) | P2RX3P2RX2 | |
| SCHEMBL19364184 | 0.73 | P2RX3 (0.42) | POLBALDH1A1GAAP2RX3P2RX2 | |
| SCHEMBL22448614 | 0.73 | KMT2A (0.33) | ALDH1A1GAAGABRA1GABRB1ALOX15 | |
| SCHEMBL25484238 | 0.72 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL22448625 | 0.72 | MAPK1 (0.47) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964505-A1 | SOLID FORM OF DIAMINOPYRIMIDINE COMPOUND OR HYDRATE THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| EP-3712144-A1 | P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |