Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620582 | 0.86 | RAD51 (0.47) | CFTRKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL17620557 | 0.80 | KDM4E (0.40) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL17620562 | 0.80 | RAB9A (0.40) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL22449448 | 0.79 | KDM4E (0.40) | KMT2AMEN1MAPTSMN1; SMN2TNK2 | |
| SCHEMBL22449438 | 0.77 | RAD51 (0.50) | KMT2AMEN1MAPTSMN1; SMN2TNK2 | |
| SCHEMBL22449433 | 0.77 | MEN1 (0.49) | KMT2AMEN1TNK2ALDH1A1 | |
| SCHEMBL17620569 | 0.77 | CYP19A1 (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17620578 | 0.77 | TDP1 (0.49) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL21656455 | 0.77 | RAD51 (0.38) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL17620587 | 0.77 | KDM4E (0.49) | KMT2AMEN1SMN1; SMN2RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787448-B2 | Indolizino [3,2-C] quinoline-based fluorescent probe | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787448-B2 | Indolizino [3,2-C] quinoline-based fluorescent probe | DNA2, IRF3, DDB1 | CFTR 4126/4885KMT2A 3767/4885MEN1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.