Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22444290 | 0.88 | ALOX5AP (0.45) | ALOX5APFEN1ABL1KCNH2MPO | |
| Hydrochloric Acid SCHEMBL22444193 | 0.86 | ALOX5AP (0.44) | ALOX5APFEN1ABL1KCNH2MPO | |
| SCHEMBL21426824 | 0.81 | MAOA (0.44) | ALOX5APFEN1ABL1KCNH2GABBR2 | |
| SCHEMBL2555064 | 0.77 | ALOX5AP (0.45) | ALOX5APFEN1ABL1KCNH2SCN10A | |
| SCHEMBL21426828 | 0.76 | JAK2 (0.48) | ALOX5APFEN1ABL1KCNH2JAK2 | |
| SCHEMBL21426829 | 0.73 | FFAR4 (0.39) | FFAR4ABL1SCN10ASCN5AFFAR1 | |
| SCHEMBL18654126 | 0.72 | LTA4H (0.56) | ALOX5APFEN1KCNH2SCN10ASCN1A | |
| SCHEMBL1550503 | 0.71 | SCN5A (0.44) | ALOX5APFEN1FFAR4ABL1SCN10A | |
| SCHEMBL29655522 | 0.71 | DHFR (0.53) | ALOX5APFEN1KCNH2SCN10ASCN1A | |
| SCHEMBL1388613 | 0.71 | DHFR (0.53) | ALOX5APFEN1KCNH2SCN10ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188833-A1 | MANUFACTURING METHOD FOR BIARYL AMIDE DERIVATIVE | 持田製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |