Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 1.00 |
| ▸ | RORA | P35398 | 2/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451941 | 0.91 | RORC (1.00) | RORCRORANR1H4 | |
| SCHEMBL19166608 | 0.88 | RORC (0.81) | RORCRORANR1H4 | |
| SCHEMBL19165251 | 0.88 | RORC (0.84) | RORCRORANR1H4 | |
| SCHEMBL17114558 | 0.86 | RORC (0.80) | RORCRORA | |
| SCHEMBL22451906 | 0.86 | RORC (1.00) | RORCRORANR1H4 | |
| SCHEMBL19165424 | 0.86 | RORC (0.81) | RORCRORANR1H4 | |
| SCHEMBL19165858 | 0.86 | RORC (0.81) | RORCRORANR1H4 | |
| SCHEMBL29832886 | 0.86 | RORC (1.00) | RORCRORANR1H4 | |
| SCHEMBL24032689 | 0.85 | RORC (0.76) | RORCRORANR1H4 | |
| SCHEMBL19165254 | 0.84 | RORC (1.00) | RORCRORANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251027-A1 | BENZIDINE COMPOUND AND APPLICATION THEREOF | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2022-08-11 | — | — | US | claimed |
| US-12297164-B2 | Benzidine compound and application thereof | GUANGZHOU IMD THERAPEUTICS CO., LTD. (CN) | 2025-05-13 | — | — | US | disclosed |
| CN-113666853-B | Biaryl compounds useful as ROR gamma modulators | 上海辉启生物医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20220251027-A1 | BENZIDINE COMPOUND AND APPLICATION THEREOF | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2022-08-11 | — | — | US | disclosed |
| WO-2021228215-A1 | BIARYL COMPOUND CAPABLE OF SERVING AS RORγ REGULATOR | 上海辉启生物医药科技有限公司 | 2021-11-18 | — | — | WO | disclosed |
| WO-2020186632-A1 | BENZIDINE COMPOUND AND APPLICATION THEREOF | 中国科学院广州生物医药与健康研究院 | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251027-A1 | BENZIDINE COMPOUND AND APPLICATION THEREOF | RORC, RORB, RORA | RORC 1/4885RORA 3/4885NR1H4 29/4885 |
| US-12297164-B2 | Benzidine compound and application thereof | RORC, RORB, RORA | RORC 1/4885RORA 3/4885NR1H4 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.