Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452457 | 0.94 | MEN1 (0.52) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452960 | 0.93 | DHODH (0.45) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452867 | 0.91 | MEN1 (0.49) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452874 | 0.89 | DHODH (0.54) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452720 | 0.88 | MEN1 (0.60) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22453258 | 0.87 | MEN1 (0.49) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22453181 | 0.87 | TUBB4A (0.45) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452913 | 0.84 | LIPE (0.44) | DHODHMEN1LMNAKMT2APOLB | |
| SCHEMBL22452865 | 0.82 | DHODH (0.49) | DHODHAKR1C3AKR1C2MEN1LMNA | |
| SCHEMBL22452887 | 0.80 | AKR1C3 (0.48) | DHODHAKR1C3AKR1C2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |