Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 16/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452504 | 0.84 | HIF1A (0.43) | NAMPTACACBFFAR4GFER | |
| SCHEMBL22453367 | 0.76 | ACACB (0.38) | NAMPTACACB | |
| SCHEMBL22452465 | 0.68 | KDM4C (0.39) | GFER | |
| SCHEMBL22453037 | 0.68 | HIF1A (0.50) | — | |
| SCHEMBL22453056 | 0.68 | KDM4C (0.37) | GFER | |
| SCHEMBL22452516 | 0.66 | HIF1A (0.47) | — | |
| SCHEMBL22452491 | 0.66 | HIF1A (0.42) | — | |
| SCHEMBL22452819 | 0.64 | HIF1A (0.41) | — | |
| SCHEMBL28673995 | 0.64 | LMNA (0.57) | — | |
| SCHEMBL29698736 | 0.64 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |