Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453582 | 0.90 | KDM4C (0.41) | KDM4CKDM4ELMNANPC1RAB9A | |
| SCHEMBL22453259 | 0.88 | KDM4C (0.44) | KDM4CKDM6BKDM4ELMNASCN9A | |
| SCHEMBL22453579 | 0.80 | CYP1A2 (0.42) | KDM4CKDM6BKDM4ELMNANPC1 | |
| SCHEMBL22453330 | 0.78 | KDM4C (0.47) | KDM4CKDM4ELMNASMN1; SMN2 | |
| SCHEMBL22452558 | 0.76 | KDM4C (0.42) | KDM4CKDM6BKDM4ELMNASMN1; SMN2 | |
| SCHEMBL22453406 | 0.74 | CYP1A2 (0.44) | KDM4CKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL22453260 | 0.71 | LTC4S (0.44) | KDM4ELMNASCN9A | |
| SCHEMBL22452446 | 0.70 | KDM4C (0.46) | KDM4CKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL22453288 | 0.69 | MEN1 (0.57) | KDM4CLMNASMN1; SMN2 | |
| SCHEMBL22452931 | 0.68 | S100B (0.46) | KDM4CKDM4ELMNASCN9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |