Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453582 | 0.90 | KDM4C (0.41) | CYP1A2KDM4CMAPTTP53MTNR1A | |
| SCHEMBL22453259 | 0.90 | KDM4C (0.44) | KDM4CKDM6BKDRSCN10AKDM4E | |
| SCHEMBL22453576 | 0.81 | CYP1A2 (0.40) | CYP1A2KDM4CKDM6BMAPTMTNR1A | |
| SCHEMBL22453261 | 0.80 | KDM4C (0.46) | KDM4CKDM6BKDM4ENPC1RAB9A | |
| SCHEMBL22453580 | 0.77 | DHODH (0.50) | CYP1A2MAPTMTNR1AMTNR1BKDR | |
| SCHEMBL22452936 | 0.73 | NR1H4 (0.35) | CYP1A2MAPTTP53SMN1; SMN2 | |
| SCHEMBL22452953 | 0.71 | TUBB4A (0.44) | CYP1A2KDM4CKDM6BMAPTMTNR1A | |
| SCHEMBL22453458 | 0.71 | MEN1 (0.46) | KDM4CKDM6BMAPTPOLBSMN1; SMN2 | |
| SCHEMBL18002733 | 0.70 | MAPT (0.46) | CYP1A2MAPTSCN10APOLBKDM4E | |
| SCHEMBL31670732 | 0.68 | CYP1A2 (0.66) | CYP1A2MAPTPOLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |