SCHEMBL2245334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2245347	0.86	CA12 (0.50)	KDM4EALDH1A1HSD17B10HPGDCA12
	SCHEMBL2245557	0.86	CA12 (0.50)	KDM4EALDH1A1HSD17B10HPGDCA12
	SCHEMBL2243664	0.83	CA12 (0.49)	KDM4EALDH1A1HSD17B10HPGDCA12
	SCHEMBL2247305	0.83	SIGMAR1 (0.36)	L3MBTL1KDM4EALDH1A1POLBKMT2A
	SCHEMBL2243653	0.83	CA12 (0.39)	L3MBTL1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2247230	0.83	CA12 (0.39)	L3MBTL1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2242700	0.82	KDM1A (0.41)	L3MBTL1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2777326	0.81	ALDH1A1 (0.49)	L3MBTL1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2243354	0.81	CA12 (0.41)	KDM4EALDH1A1HSD17B10HPGDCA12
	SCHEMBL2247045	0.80	CA12 (0.52)	ALDH1A1HPGDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.