Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447464 | 0.85 | AGXT (0.41) | AGXTALDH1A1CYP11B2CYP11B1KDM4E | |
| SCHEMBL19063459 | 0.85 | PDE4D (0.42) | PDE4DALDH1A1KMT2AGAACHUK | |
| Hydrochloric Acid SCHEMBL17591666 | 0.82 | AGXT (0.39) | AGXTALDH1A1CYP11B2CYP11B1KDM4E | |
| SCHEMBL29682842 | 0.82 | AGXT (0.39) | AGXTALDH1A1CYP11B2CYP11B1KDM4E | |
| SCHEMBL15859005 | 0.76 | ACHE (0.41) | AGXTALDH1A1CYP11B2CYP11B1KDM4E | |
| SCHEMBL24899923 | 0.74 | AGXT (0.35) | AGXTCYP11B2CYP11B1CYP1A1CYP1B1 | |
| SCHEMBL14225088 | 0.74 | PDE4D (0.37) | PDE4DALDH1A1KMT2AGAACHUK | |
| SCHEMBL13724673 | 0.74 | CA2 (0.37) | AGXTCYP11B2CYP11B1CYP1A1CYP1B1 | |
| SCHEMBL19616148 | 0.74 | AGXT (0.39) | AGXTALDH1A1CYP11B2CYP11B1GAA | |
| SCHEMBL27387671 | 0.74 | CYP11B2 (0.41) | AGXTCYP11B2CYP11B1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191091-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2020-09-24 | — | — | WO | disclosed |