Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2358777 | 0.88 | CYP2B6 (0.37) | ESR1ESR2CYP2B6MAPK1 | |
| Hydrochloric Acid SCHEMBL2245514 | 0.82 | MEN1 (0.31) | CYP2B6MEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL2357987 | 0.80 | KCNN4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2240349 | 0.79 | KIF11 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29205577 | 0.76 | ALDH1A1 (0.38) | ALDH1A1ESR1CYP3A4ESR2CYP2B6 | |
| SCHEMBL28478551 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ESR1CYP3A4ESR2CYP2B6 | |
| Hydrochloric Acid SCHEMBL2245918 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL16568996 | 0.73 | ALDH1A1 (0.38) | ALDH1A1ESR1CYP3A4ESR2CYP2B6 | |
| Hydrochloric Acid SCHEMBL6814153 | 0.73 | ALDH1A1 (0.38) | ALDH1A1ESR1CYP3A4ESR2CYP2B6 | |
| SCHEMBL3838181 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207977-A1 | METHOD FOR PRODUCING A-OLEFIN OLIGOMER, A-OLEFIN OLIGOMER, AND LUBRICATING OIL COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2351722-A1 | METHOD FOR PRODUCING -OLEFIN OLIGOMER, -OLEFIN OLIGOMER, AND LUBRICATING OIL COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207977-A1 | METHOD FOR PRODUCING A-OLEFIN OLIGOMER, A-OLEFIN OLIGOMER, AND LUBRICATING OIL COMPOSITION | MOGAT2, OSBP, OXER1 | ALDH1A1 2083/4885ESR1 2277/4885CYP3A4 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.