Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22458033 | 1.00 | HTR2A (0.31) | HTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL2994718 | 0.76 | HTR2C (0.56) | HTR2AHTR2CHTR2B | |
| SCHEMBL12024874 | 0.75 | — | — | |
| SCHEMBL22458037 | 0.73 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL13845087 | 0.69 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL22458036 | 0.65 | — | — | |
| SCHEMBL22458038 | 0.65 | — | — | |
| SCHEMBL31563807 | 0.63 | DRD2 (0.38) | L3MBTL1 | |
| SCHEMBL31563923 | 0.63 | DRD2 (0.38) | L3MBTL1 | |
| SCHEMBL31564100 | 0.63 | DRD2 (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219974-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| US-11560388-B2 | Anthelmintic aza-benzothiophene and aza-benzofuran compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH | 2023-01-24 | — | — | US | disclosed |
| US-20200299304-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299304-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | TPMT, NAT1, HNMT | HTR2A 3328/4885HTR2C 1814/4885HTR2B 2193/4885 |
| US-11560388-B2 | Anthelmintic aza-benzothiophene and aza-benzofuran compounds | TPMT, NAT1, HNMT | HTR2A 3328/4885HTR2C 1814/4885HTR2B 2193/4885 |
| US-20230219974-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | TPMT, NAT1, HNMT | HTR2A 3328/4885HTR2C 1814/4885HTR2B 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.