SCHEMBL22459645

SCHEMBL22459645

c1ccc(-c2ccc(-n3c4ccccc4c4cc5c6ccccc6n(-c6ncc(-c7ccccc7)cn6)c5cc43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.39
RAC2 P15153 1/20 0.35
RAC3 P60763 1/20 0.35
CDC42 P60953 1/20 0.35
RAC1 P63000 1/20 0.35
NPC1 O15118 2/20 0.35
NFKB1 P19838 2/20 0.35
RAB9A P51151 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24490408 0.99 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL22459644 0.97 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL24490394 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL24490206 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL22459657 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL18708361 0.96 L3MBTL1 (0.51) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL24490407 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL24490204 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4NPC1
SCHEMBL24490397 0.93 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL24490409 0.93 NPC1 (0.40) L3MBTL1KDM4EATMRAC2RAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-03 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-05-16 US disclosed
US-20220181558-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-06-09 US disclosed
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299274-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 L3MBTL1 48/4885KDM4E 1410/4885ATM 2066/4885
US-20230242518-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 L3MBTL1 48/4885KDM4E 1410/4885ATM 2066/4885
US-20220181558-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, LIMS1, TERT L3MBTL1 29/4885KDM4E 3609/4885ATM 2823/4885
US-11649225-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 L3MBTL1 48/4885KDM4E 1410/4885ATM 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.