Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RECQL | P46063 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089541 | 0.75 | ADRA1A (0.55) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL9089549 | 0.75 | ADRA1A (0.55) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL16216157 | 0.70 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL13158583 | 0.67 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL1691820 | 0.67 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL15631290 | 0.64 | ADRA1A (0.54) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL5393005 | 0.64 | BCHE (0.33) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL20366920 | 0.63 | CYP2D6 (0.37) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL12287584 | 0.62 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL6285589 | 0.62 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299227-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF DROXIDOPA AND ITS INTERMEDIATE | Piramal Enterprises Limited (IN) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299227-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF DROXIDOPA AND ITS INTERMEDIATE | COMT, DAO, DDO | ADRA2A 90/4885ADRA2B 116/4885ADRA2C 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.